You can easily get to San Telmo area by taxi (remember to take the ones that have the “Radio Taxi” sign), and if you want a point of reference you can tell the taxi driver to drop you off either at Plaza Dorrego or Mercado de San Telmo. Remember to have some pocket money with you and that taxis are metered: whatever it shows on the meter will be the total price to be paid in Argentine pesos.
As San Telmo is the smallest district in Buenos Aires, everything is located within walking distance.
The nearest subway station is Independencia, on the E and C lines, on the edge of San Telmo. Walk along Independencia Ave. towards the river for six blocks and then turn right at Defensa St. for another four blocks to get to Plaza Dorrego. You can also head to Plaza de Mayo, with access to the A and D metro lines. On Sundays, the street market goes along Defensa for almost 10 blocks all the way to Plaza de Mayo.
If you want to delve beneath the surface of Buenos Aires city while seeing San Telmo and other major attractions leaving the organization up to someone else check out our Small-Group Buenos Aires City Tour, a great tour to do if you want to get a good feeling of the city and discover places to keep exploring afterward.
Another possibility could be booking a private tour, which is more convenient if you want to have a fully customized experience based on your particular interests, have a closed tour exclusively for your travel group, and have all of the tour guide’s attention for yourself. If this is the case, we recommend you to take a look at both our Private Highlights of Buenos Aires Tour and our Private Customizable Walking Tour to see which option is best suited for your needs and budget.